 | • レポートコード：MRC2303B041 • 出版社/出版日：Mordor Intelligence / 2023年3月 • レポート形態：英文、PDF、114ページ • 納品方法：Eメール（受注後2-3営業日） • 産業分類：医療 |
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レポート概要
| Mordor Intelligence社の市場調査書では、世界のタンパク質安定性分析市場規模が予測期間中に年平均3.5％上昇すると推測されています。本調査書では、タンパク質安定性分析の世界市場を広く調査・分析をし、イントロダクション、調査手法、エグゼクティブサマリー、市場動向、製品別（試薬・アッセイキット、器具、消耗品・付属品、その他）分析、技術別（クロマトグラフィー、分光法、表面プラズモン共鳴、示差走査熱量測定、その他）分析、エンドユーザー別（製薬・バイオテクノロジー企業、学術・研究機関）分析、地域別（アメリカ、カナダ、メキシコ、ドイツ、イギリス、フランス、イタリア、スペイン、中国、日本、インド、オーストラリア、韓国、中東、南アフリカ、ブラジル、アルゼンチン）分析、競争状況、市場機会・将来動向などを整理しています。また、本書には、Agilent Technologies, Inc.、NanoTemper Technologies、Horiba, Ltd、Perkinelmer, Inc.、Setaram Instrumentation、Shimadzu Corporation、Spectris PLC、Thermo Fisher Scientific、Unchained Labsなどの企業情報が含まれています。 ・イントロダクション ・調査手法 ・エグゼクティブサマリー ・市場動向 ・世界のタンパク質安定性分析市場規模：製品別 - 試薬・アッセイキットの市場規模 - 器具の市場規模 - 消耗品・付属品の市場規模 - その他タンパク質安定性分析の市場規模 ・世界のタンパク質安定性分析市場規模：技術別 - クロマトグラフィータンパク質安定性分析の市場規模 - 分光法タンパク質安定性分析の市場規模 - 表面プラズモン共鳴法タンパク質安定性分析の市場規模 - 示差走査熱量測定法タンパク質安定性分析の市場規模 - その他タンパク質安定性分析の市場規模 ・世界のタンパク質安定性分析市場規模：エンドユーザー別 - 製薬・バイオテクノロジー企業における市場規模 - 学術・研究機関における市場規模 ・世界のタンパク質安定性分析市場規模：地域別 - 北米のタンパク質安定性分析市場規模 アメリカのタンパク質安定性分析市場規模 カナダのタンパク質安定性分析市場規模 メキシコのタンパク質安定性分析市場規模 … - ヨーロッパのタンパク質安定性分析市場規模 ドイツのタンパク質安定性分析市場規模 イギリスのタンパク質安定性分析市場規模 フランスのタンパク質安定性分析市場規模 … - アジア太平洋のタンパク質安定性分析市場規模 中国のタンパク質安定性分析市場規模 日本のタンパク質安定性分析市場規模 インドのタンパク質安定性分析市場規模 … - 南米/中東のタンパク質安定性分析市場規模 南アフリカのタンパク質安定性分析市場規模 ブラジルのタンパク質安定性分析市場規模 アルゼンチンのタンパク質安定性分析市場規模 … ・競争状況 ・市場機会・将来動向 |
The protein stability analysis market is expected to register a CAGR of 3.5% during the forecast period.
COVID-19 had a significant impact on the protein stability analysis market in the initial phase since protein stability studies were conducted to assess the structure and nature of the COVID-19 virus to a great extent which helps gain a better understanding of the virus and supports the development of effective and efficient therapeutics. For instance, as per the article published in September 2022 in Stanford Medicine, elevated virus levels in the blood of COVID-19 patients in hospitals predicted the worsening of respiratory symptoms and suggest ongoing viral replication in advanced disease stages. A protein of the virus that causes COVID-19 was measured in the patient’s blood during the test. Hence, such analysis showing the complications associated with COVID-19 through protein analysis will likely boost the market growth.
In the post-pandemic era, studies are still being conducted due to the emergence of different COVID-19 mutants. Since the beginning of the pandemic, the WHO has described eight variants of interest (VOIs), namely Epsilon, Zeta, Eta, Theta, Iota, Kappa, Lambda, and Mu. Currently, studies are being conducted to determine whether mutants of Omicron variants affect the virus’s properties, speed of spreading, the severity of the associated disease, the performance of vaccines, or other public health and social measures and hence, the demand for protein analysis products is expected to increase. Another factor to account for are the Sars-COV-2 strains which are expected to have a positive impact on the market over the forecast period.
Factors such as rising research and development expenditure of pharmaceutical and biopharmaceutical companies, increasing proteomics and genomics research activities, and an increasing number of recombinant protein therapeutics and biologics are expected to drive the market growth over the forecast period since research studies require protein stability assessments to substantiate the results.
For instance, as per the EFPIA 2022 report, in 2021, Europe invested an estimated EUR 41,500 million (about USD 35,109 million) in pharmaceutical R&D. Thus, huge investments in R&D drive the growth of the protein stability analysis market during the forecast period. Furthermore, investments and financing in genomic research activities are projected to fuel the market as researchers seek opportunities in protein stability studies. For instance, in September 2022 NHGRI, part of the NIH, planned to fund USD 3.35 million over five years to launch the Genome Research Experiences to attract researchers into the Genomics Field to Enhance Diversity (GREAT) program. Moreover, in September 2022, a joint venture by the University of Western Australia and Proteomics International, which conducts vital work in medical, environmental, and agricultural testing of proteins received a funding of USD 2 million . The money is likely to enable the WA Proteomics Facility to upgrade its automated tools and staff, increasing output capacity to hundreds of samples.
As a result of the increase in pharmaceutical and biopharmaceutical companies’ R&D expenditures, as well as the increase in the number of proteomics and genomics research activities, the protein stability analysis market is anticipated to witness growth over the forecast period. However, the high cost of protein stability analysis systems is expected to restrain the growth of this market to a certain extent.
Protein Stability Analysis Market Trends
Differential Scanning Calorimetry (DSC) is Expected to Hold a Significant Share Over the Forecast Period
The differential scanning calorimetry technique has been widely used in characterizing the stability of proteins in their native form by measuring the heat required to denature a particular biomolecule, like a protein. This technique determines molecules with higher thermal transition midpoints, which are considered more stable than those with lower transition midpoints. This technique is widely used in research & development and drug discovery. The DSC segment is likely to witness growth over the forecast period due to the wide advantages of DSC such as the ease and speed with which it can be used to see transitions in materials. Due to this reason, DSC is preferred over other techniques to scan and identify proteins.
The research and development in the field of protein stability using differential scanning calorimetry are driving the market growth as it showcases the ease and speed of DSC for research. According to an article published in June 2022 in the Biosensors journal, a study demonstrated the direct thermal characterization of protein samples using a new micro-electromechanical system (MEMS)-based differential scanning calorimeter (DSC). With high throughput, the MEMS calorimeter could screen many therapeutic proteins for conformational stability based on transition temperature. Hence, such advancements in DSC associated with protein analysis are likely to boost market growth over the forecast period. The importance of research and development (R&D) for the pharmaceutical industry is evidenced by the cumulative R&D expenditure in the sector. It has been observed that R&D spending is increasing each year and several pharma and biotech companies are focusing on strengthening their R&D facilities which are ultimately driving the growth of the market studied. The spending on research and development (R&D) by various pharmaceutical companies and government organizations has been increasing recently in the United States, which is anticipated to drive market growth over the forecast period. For instance, as per the 2022 report from EFPIA, in 2021 North America accounted for 49.1% of world pharmaceutical sales compared with 23.4% for Europe. As the R&D expenditure and sales increase, the demand for protein stability analysis techniques like DSC is expected to increase thereby boosting the market growth.
North America is Expected to Dominate the Market During the Forecast Period
The presence of well-established research and development institutions and their high investment in the region is driving market growth over the forecast period since the research initiatives are likely to utilize protein stability studies for accurate results. For instance, as per the Statistics Canada June 2022 report, in-house spending on R&D in 2021 was expected to grow by 3.5%, reaching USD 23.4 billion. Companies expect more modest growth in their in-house R&D spending in 2022, with total R&D spending anticipated to increase by 1.7% to USD 23.8 billion.
Furthermore, investments by the government and private companies in genomic and proteomic research are likely to drive market growth in the North American region. For instance, in February 2021, through a merger, Seattle-based Nautilus Biotechnology entered the public market and received USD 350 million to accelerate the development of its protein analysis technology for drug discovery and diagnostic applications. Moreover, in September 2022, Stanford University Mass Spectrometry Proteomics Seed Grants provided a research grant of USD 10,000 to researchers aiming for new mass spectrometry projects and new methodologies taking advantage of the capabilities of recently added research instrumentation.
Additionally, genomic as well as proteomic research works in the North American region promote market growth since they identify the need for protein stability study and utilize the reagents and equipment associated with stability studies. For instance, as per the article published in May 2022 by MDPI which was supported by the National Institute of Respiratory Diseases “Ismael Cosío Villegas,” Mexico, a study showed that proteomics has enabled the identification of novel allergens that can be used in serodiagnosis and has made it possible to analyze thousands of proteins in a single analysis.
Protein Stability Analysis Market Competitor Analysis
The protein stability analysis market is fragmented in nature due to the presence of several companies operating globally as well as regionally. The competitive landscape includes an analysis of a few international and local companies that hold market shares and are well-known. These include Agilent Technologies Inc, NanoTemper Technologies, Shimadzu Corporation, Thermo Fisher Scientific, and Spectris PLC (Malvern Panalytical Ltd).
Additional Benefits:
- The market estimate (ME) sheet in Excel format
- 3 months of analyst support
1 INTRODUCTION
1.1 Study Assumptions and Market Definition
1.2 Scope of the Study
2 RESEARCH METHODOLOGY
3 EXECUTIVE SUMMARY
4 MARKET DYNAMICS
4.1 Market Overview
4.2 Market Drivers
4.2.1 Rising Research and Development Expenditure of Pharmaceutical and Biopharmaceutical Companies
4.2.2 Increasing Proteomics and Genomics Research Activities
4.2.3 Increasing Number of Recombinant Protein Therapeutics and Biologics
4.3 Market Restraints
4.3.1 High Cost of Protein Stability Analysis Instruments
4.4 Porter’s Five Forces Analysis
4.4.1 Bargaining Power of Suppliers
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Threat of New Entrants
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5 MARKET SEGMENTATION (Market Size by Value – USD Million)
5.1 By Product
5.1.1 Reagents and Assay Kits
5.1.2 Instruments
5.1.3 Consumables and Accessories
5.1.4 Other Products
5.2 By Technique
5.2.1 Chromatography
5.2.2 Spectroscopy
5.2.3 Surface Plasmon Resonance
5.2.4 Differential Scanning Calorimetry
5.2.5 Differential Scanning Fluorimetry
5.2.6 Other Techniques
5.3 By End-User
5.3.1 Pharmaceutical & Biotechnology Companies
5.3.2 Academic and Research Organizations
5.4 Geography
5.4.1 North America
5.4.1.1 United States
5.4.1.2 Canada
5.4.1.3 Mexico
5.4.2 Europe
5.4.2.1 Germany
5.4.2.2 United Kingdom
5.4.2.3 France
5.4.2.4 Italy
5.4.2.5 Spain
5.4.2.6 Rest of Europe
5.4.3 Asia-Pacific
5.4.3.1 China
5.4.3.2 Japan
5.4.3.3 India
5.4.3.4 Australia
5.4.3.5 South Korea
5.4.3.6 Rest of Asia-Pacific
5.4.4 Middle East
5.4.4.1 GCC
5.4.4.2 South Africa
5.4.4.3 Rest of Middle East
5.4.5 South America
5.4.5.1 Brazil
5.4.5.2 Argentina
5.4.5.3 Rest of South America
6 COMPETITIVE LANDSCAPE
6.1 Company Profiles
6.1.1 Agilent Technologies, Inc.
6.1.2 NanoTemper Technologies
6.1.3 Horiba, Ltd
6.1.4 Perkinelmer, Inc.
6.1.5 Setaram Instrumentation
6.1.6 Shimadzu Corporation
6.1.7 Spectris PLC
6.1.8 Thermo Fisher Scientific
6.1.9 Unchained Labs
6.1.10 Danaher Corporation (Molecular Devices)
6.1.11 Spectris PLC (Malvern Panalytical Ltd)
6.1.12 Bruker Corporation
7 MARKET OPPORTUNITIES AND FUTURE TRENDS